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Home >
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Vitamin B-5 |
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Supplement Articles |
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VITAMIN B-5 PANTETHINE ACID
Articles by a Naturopathic
Doctor ( N.D.)
The active coenzyme form of vitamin B5… |
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Pantethine is made up of two pantothenic acid (vitamin B5) molecules, and is considered to be a more biologically active form of vitamin B5. Unfortunately, it is also less stable than pantothenic acid, and will degrade over time if not kept refrigerated. Unlike other forms of vitamin B5, pantethine is the only form that has been shown to have blood lipid and cholesterol balancing properties. |
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Cholesterol and Blood Lipids
Pantethine has been shown to lower LDL ("bad") cholesterol, while raising the levels of HDL ("good") cholesterol. This effect is especially seen in individuals with diabetes. It has also been shown to slightly lower triglyceride levels. All of these effects were seen in people with moderate to severe dyslipidemia (cholesterol and lipid imbalances).
Use in Diabetes and Kidney Failure
Vitamin B5, in the form of pantethine, has been shown to have particularly beneficial effect to the cholesterol levels of diabetics, over and above the benefits to others experiencing dyslipidemia. Interestingly, pantethine also appears to correct blood lipid problems that occur in people undergoing hemodialysis for kidney failure.
How can I take pantethine?
The benefits of pantethine seem to be outside of its ability to be a precursor for vitamin B5. Because pantethine is not very shelf stable, generally vitamin B5 is supplemented using the calcium pantothenate form. For its cholesterol-balancing benefits, pantethine is supplemented between 300 and 1200 mg per day.
Important Information
Supplementation of pantethine may cause nausea, diarrhea, and stomach discomfort. It may also slow blood clotting so avoid use if you have a bleeding disorder or are on blood thinning medication. Supplementation should be stopped at least 1 week prior to surgery for the same reason. |
VITAMIN B5 –
QUICK FACTS
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APPLICATIONS |
· Dyslipidemia: high cholesterol, high triglycerides. |
OPTIMUM
DOSAGE
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· 300 - 1200 mg daily. (Clinical doses may be higher as recommended by your practitioner). |
WORKS WELL
WITH
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Fibre supplementation, B complex, Hawthorn berry.
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IMPORTANT INFORMATION
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· Supplementation may cause nausea, diarrhea, or stomach discomfort.
· Pantethine may slow blood clotting and should not be used if you have a blood clotting disorder or are on blood thinning medications.
· Supplementation should be stopped at least 1 week prior to surgery. |
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