Sam-E
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NATURAL FACTORS SAM-E AN OPTIMAL 200MG POTENCY FOR MOOD AND JOINT HEALTH. Clinical studies suggest that Sam-e may offer positive benefits for those who suffer from mild depression and sore joints. Natural Factors Sam-E provides a 200 mg dosage of S-Adenosyl-L-Methioninie (Sam-E) from 400 mg of SAM-e Disulfate Tosylate. Sam-E is impor...NATURAL FACTORS SAM-E AN OPTIMAL 200MG POTENCY FOR MOOD AND JOINT HEALTH. Clinical studies suggest that Sam-e may offer positive benefits for those who suffer from mild depression and sore joints. Natural Factors Sam-E provides a 200 mg dosage of S-Adenosyl-L-Methioninie (Sam-E) from 400 mg of SAM-e Disulfate Tosylate. Sam-E is important for the production of certain neurotransmitters in the brain and is actively involved with Folic Acid and Vitamin B12 to promote healthy brain function. Sam-e has also been shown to be an important factor in the production of glucosamine and chondroitin making it an essential component to joint health. [TABLET]+ Earn 26 Reward Points
Sale: $26.99
Reg.: $34.99 (Save $8.00)
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NATURAL FACTORS SAM-E AN OPTIMAL 200MG POTENCY FOR MOOD AND JOINT HEALTH. Clinical studies suggest that Sam-e may offer positive benefits for those who suffer from mild depression and sore joints. Natural Factors Sam-E provides a 200 mg dosage of S-Adenosyl-L-Methioninie (Sam-E) from 400 mg of SAM-e Disulfate Tosylate. Sam-E is impor...NATURAL FACTORS SAM-E AN OPTIMAL 200MG POTENCY FOR MOOD AND JOINT HEALTH. Clinical studies suggest that Sam-e may offer positive benefits for those who suffer from mild depression and sore joints. Natural Factors Sam-E provides a 200 mg dosage of S-Adenosyl-L-Methioninie (Sam-E) from 400 mg of SAM-e Disulfate Tosylate. Sam-E is important for the production of certain neurotransmitters in the brain and is actively involved with Folic Acid and Vitamin B12 to promote healthy brain function. Sam-e has also been shown to be an important factor in the production of glucosamine and chondroitin making it an essential component to joint health. [TABLET]+ Earn 49 Reward Points
Sale: $49.99
Reg.: $64.99 (Save $15.00)
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SAME 400MG FOR MOOD & JOINT SUPPORT. SAMe 400 is a key biological factor that drives a wide variety of essential biochemical reactions, including the methylation of DNA, catecholamine neurotransmitters (brain messenger-molecules), phospholipids, hormones, and chondrocytes (cartilage-forming cells). Research suggests SAMe's ability to ...SAME 400MG FOR MOOD & JOINT SUPPORT. SAMe 400 is a key biological factor that drives a wide variety of essential biochemical reactions, including the methylation of DNA, catecholamine neurotransmitters (brain messenger-molecules), phospholipids, hormones, and chondrocytes (cartilage-forming cells). Research suggests SAMe's ability to support healthy mood function and to relieve symptoms and reduce functional impairment in osteoarthritis. SAMe 400 provides a full 400 mg of true SAMe ion per tablet, with a minimum of 70% biologically active (S),S-diastereoisomer. [TABLET]+ Earn 61 Reward Points
Sale: $61.52
Reg.: $76.78 (Save $15.26)
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SAME 400MG FOR MOOD & JOINT SUPPORT SAMe 400 is a key biological factor that drives a wide variety of essential biochemical reactions, including the methylation of DNA, catecholamine neurotransmitters (brain messenger-molecules), phospholipids, hormones, and chondrocytes (cartilage-forming cells). Research suggests SAMe's ability to s...SAME 400MG FOR MOOD & JOINT SUPPORT SAMe 400 is a key biological factor that drives a wide variety of essential biochemical reactions, including the methylation of DNA, catecholamine neurotransmitters (brain messenger-molecules), phospholipids, hormones, and chondrocytes (cartilage-forming cells). Research suggests SAMe's ability to support healthy mood function and to relieve symptoms and reduce functional impairment in osteoarthritis. SAMe 400 provides a full 400 mg of true SAMe ion per tablet, with a minimum of 70% biologically active (S),S-diastereoisomer. [TABLET]+ Earn 101 Reward Points
Sale: $101.94
Reg.: $127.24 (Save $25.30)
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NERVOUS SYSTEM SUPPORT & OSTEOARTHRITIS SAMe (S-adenosylmethionine), a compound native to the body, is a critical component of many biochemical reactions, including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can help to temporarily alleviate minor joint discomfort resulting from ov...NERVOUS SYSTEM SUPPORT & OSTEOARTHRITIS SAMe (S-adenosylmethionine), a compound native to the body, is a critical component of many biochemical reactions, including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can help to temporarily alleviate minor joint discomfort resulting from overexertion or stress. In addition, because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in mood support. NOW SAMe is enteric-coated, which makes it very well tolerated and protects it from degradation. [TABLETS]+ Earn 49 Reward Points
Sale: $49.99
Reg.: $69.99 (Save $20.00)
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SAMe is a key biological factor that drives a wide variety of essential biochemical reactions, including the methylation of DNA, catecholamine neurotransmitters (brain messenger-molecules), phospholipids, hormones, and chondrocytes (cartilage-forming cells). Research suggests SAMe's ability to support healthy mood function and to relie...SAMe is a key biological factor that drives a wide variety of essential biochemical reactions, including the methylation of DNA, catecholamine neurotransmitters (brain messenger-molecules), phospholipids, hormones, and chondrocytes (cartilage-forming cells). Research suggests SAMe's ability to support healthy mood function and to relieve symptoms and reduce functional impairment in osteoarthritis. [TABS]+ Earn 49 Reward Points
Sale: $49.49
Reg.: $62.49 (Save $13.00)
SAM-e, What Is It?
Did you know that in Europe SAM-e is available only by recommendation? Indeed, SAM-e (or s-adenosylmethionine) is used extensively throughout Europe as an antidepressant, as well as for the treatment of arthritis and degenerative joint conditions. So what exactly is it?
Sold as a Natural Health Product in Canada, S-adenosylmethionine (SAMe) is an endogenous metabolite – meaning that it’s made inside the body. It's your brain that synthesizes SAM-e from methionine, an essential amino acid, and adenosine triphosphate, an organic compound that serves as an energy currency for your cells. This nutrient is involved in a variety of metabolic processes in the body, and it plays an important role in the formation, activation, and breakdown of many hormones and proteins.
It also increases the turnover of serotonin (a hormone that stabilizes our mood, feelings of well-being, and happiness), increases dopamine (a feel-good neurotransmitter that is central to the pleasure and reward center of our brain), and norepinephrine. These effects on hormones and neurotransmitters may be one of the reasons why the SAMe supplementation is so effective at elevating mood and regulating behavior.
SAM-e also helps stimulate the production of cartilage – which is central halting and eventually reversing the disease process, as well as stimulates the production of glucosamine and chondroitin – compounds that are required to maintain and protect joint health. Moreover, it has well-documented pain-relieving properties. Clinical studies have shown that these supplements help to naturally reduce inflammation, and control joint pain and stiffness.
Benefits of SAM-e
- Elevates Moods & Supports Cognitive Function
- Supports Arthritis & Degenerative Joint Conditions
Who Needs SAM-e Supplements?
This nutrient is widely available in health food stores and online and may be recommended to you by your naturopath. Some of the most common uses for SAM-e include mood-based conditions, liver disease, osteoarthritis and other pain-related conditions, as well as to help improve brain function and calm allergy symptoms.
SAM-e Supplements & Formats
Potencies
SAM-e is sold in different potencies, most commonly in 200 to 400 mg. The recommended daily dose for healthy mood balance and mood-based symptoms is usually in the 1000-1600 mg range. Whereas for arthritis and degenerative joint conditions, the recommendation is 400 mg three times daily.
It’s recommended to start with a smaller dose and increase the dosage slowly until you find the appropriate dose for you.
Forms
SAM-e as an ion is unstable and has low bioavailability. Look for one of the following forms when selecting your SAM-e:
- SAM-e SAMe tosylate
- SAM-e Disulfate Tosylate
- SAMe 1,4 -butanedisulfonate.
Formats
SAM-e is sold primarily in capsule and tablet form – many being coated to enhance stability and bioavailability. SAM-e can also be found in powder form.
It pairs well with Folic Acid and Vitamin B12, to promote healthy brain function.
If you're using SAM-e to support joint health, then using it along with glucosamine or NEM will often produce better results than using them on their own.
Final Thoughts
When starting to supplement with this nutrient, read the label carefully to determine the best dosage for the condition or symptom you are taking it for. Always take SAM-e on an empty stomach. Also, note that SAM-e is stimulating so should not be taken late in the day or before bed.
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