Homocysteine Fighters

How To Maintain Healthy Homocysteine Levels

Homocysteine is a naturally occurring sulphur-containing amino acid produced during the breakdown of dietary protein, especially methionine. It is an intermediate in the methionine cycle, a series of chemical reactions essential for various physiological functions, including DNA synthesis, neurotransmitter production, and the regulation of homocysteine itself. Read more >

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  1. B-6 B-12 + Folic Acid - 110 Tabs
    This trio of vitamins work synergistically and support cardiovascular health by helping to control and reduce homocysteine levels. Adrien Gagnon’s B6, B12 + Folic Acid can help reduce homocysteine level in the blood and promote tissue and red blood cells formation. Studies have shown that this combination can help decrease risk of spin...
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  2. Glycogenics - 60 Tabs
    GLYCOGENICS Glycogenics is an advanced balanced B-complex formula that features a blend of B vitamins and complementary nutrients. It is often recommended by natural health care practitioners to help regulate healthy homocysteine metabolism, energy levels, and a healthy stress response. [TABS]
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  3. Glycogenics - 180 Tabs
    GLYCOGENICS Glycogenics is an advanced balanced B-complex formula that features a blend of B vitamins and complementary nutrients. It is often recommended by natural health care practitioners to help regulate healthy homocysteine metabolism, energy levels, and a healthy stress response. [TABS]
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  4. TMG 1,000mg - 100 Tabs
    TMG (TRIMETHYLGLYCINE) FROM NOW FOODS. Methylation is a normal biological process that occurs in healthy human bodies every minute of every day. Methylation is an important step in the conversion of nomocysteine, a damaging amino acid, into the biologically safe and beneficial amino acid, methionine. In addition, methylation is requir...
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  5. Methylation Support - 90 V-Caps
    Methylation Support formulated by Genestra provides a combination of B vitamins, choline, and betaine to help support homocysteine level. Homocysteine is an amino acid that can be further metabolized into methionine or cysteine. Betaine also helps support liver function through its role in stimulating the production and export of very ...
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Maintaining Healthy Homocysteine Levels

Homocysteine is a naturally occurring sulphur-containing amino acid produced during the breakdown of dietary protein, especially methionine. It is an intermediate in the methionine cycle, a series of chemical reactions essential for various physiological functions, including DNA synthesis, neurotransmitter production, and the regulation of homocysteine itself. In a healthy body, homocysteine levels are tightly regulated to balance production and removal.

Best Sources of Homocysteine

Diet – Dietary intake is one of the primary sources of homocysteine. Foods rich in methionine, such as meat, fish, dairy products, and eggs, can contribute to increased homocysteine levels. However, certain foods also contain nutrients that help regulate homocysteine levels, such as folate, vitamin B6, and vitamin B12. Leafy greens, beans, lentils, and fortified cereals are examples of foods that provide these nutrients.

Endogenous Production – In addition to dietary sources, homocysteine is produced within the body during the normal metabolism of methionine. This process is tightly regulated to prevent excessive accumulation of homocysteine.

How Do Elevated Homocysteine Levels Effect Health?

Maintaining balanced homocysteine levels is critical for overall health, as elevated levels of homocysteine have been associated with various health conditions, including :

  • Cardiovascular Disease – High homocysteine levels have been linked to an increased risk of cardiovascular diseases, including coronary artery disease, stroke, and peripheral artery disease. Elevated homocysteine may contribute to the development of atherosclerosis (hardening of the arteries) by damaging the blood vessel walls and promoting plaque formation.
  • Neurological Disorders – Elevated homocysteine levels are associated with cognitive decline and an increased risk of neurodegenerative diseases, such as Alzheimer's disease. Indeed, homocysteine can damage neurons and impair cognitive function.
  • Pregnancy Complications – Elevated homocysteine during pregnancy is linked to an increased risk of preeclampsia, a condition characterized by high blood pressure and organ damage. It may also contribute to neural tube defects in the developing fetus if maternal folate levels are insufficient.
  • Osteoporosis – High homocysteine levels interfere with the formation and maintenance of healthy bone tissue and can contribute to the development of osteoporosis.

How To Keep Homocysteine Levels Balanced

Controlling homocysteine levels is essential for preventing associated health risks. Here are some strategies to achieve this:

  • Dietary Changes – A balanced diet that includes adequate amounts of folate, vitamin B6, and vitamin B12 can help regulate homocysteine levels. This entails consuming more fruits, vegetables, whole grains, and foods rich in these vitamins.
  • Lifestyle Modifications – Maintaining a healthy lifestyle that includes regular exercise, not smoking, and limiting alcohol consumption can all help reduce homocysteine levels.
  • Supplements – Various supplements, such as B vitamins combos (particularly B2, B6, B9, and B12), have been developed that can play a crucial role in helping regulate homocysteine metabolism. Trimethylglycine (TMG), also known as betaine, is another nutrient that can help lower homocysteine levels by donating a methyl group to convert homocysteine to methionine. Additionally, magnesium and choline may also be included in homocysteine-fighting supplement blends.

These supplements promote homocysteine conversion into less harmful substances, thus reducing its negative impact on health. Alongside a balanced diet and a healthy lifestyle, homocysteine-fighting supplements can be an incredibly valuable addition to one's wellness routine, helping to maintain optimal cardiovascular and cognitive health.

Why Take A Homocysteine Supporting Supplement?

Those who may benefit from homocysteine fighters include individuals with a family history of cardiovascular disease, those who have previously experienced heart-related problems, or people with specific genetic factors predisposing them to high homocysteine levels. Additionally, older adults and individuals with dietary deficiencies in vitamins B6, B12, and folate, known to regulate homocysteine levels, may also find these supplements beneficial.

Shopping For Quality Natural Health Supplements

There are quite a few homocysteine-fighting supplements available on the market. These typically come in capsule form but are also offered in tablets, powders, and liquids. Some of the most reputable include:

  • Glycogenics by Metagenics
  • TMG by NOW Foods
  • Homocysteine Supreme by Designs For Health 
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