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Home > Research Department  > Supplement Articles > 5-HTP (5 hydroxytryptophan)
    Supplement Articles  
5-HTP
Articles by a Naturopathic Doctor ( N.D.)

This natural mood support can also allow you to rest better and fight obesity ...

5-HTP

5-HTP can help you sleep better & maintain a healthy mood
5-HTP is a precursor to the hormones serotonin and melatonin.  Serotonin regulates mood, behaviour, appetite, dilation of blood vessels and many other body processes.  5-HTP has been favourably compared to tricyclic antidepressants and Prozac for its ability to alleviate depression.  Serotonin is released in response to fullness and regulates appetite.  Deficiency of serotonin can lead to overeating and obesity.  This also accounts for the fact that when we are under stress our appetite tends to change.

Some people become deficient in serotonin and gain weight because they overeat.  Others lose their appetite partly because their brain is reacting to high levels of serotonin released during the stressful time.  Serotonin also decreases the diameter of blood vessels.  This is helpful in headaches and migraines that are caused by increased blood flow in the brain.

Melatonin regulates the body’s sleep/wake cycles.  Optimal levels of melatonin allow us to have restful and restorative sleep.  Melatonin also cues the body to release growth hormone and sex hormones, which are used during sleep to repair body tissues and normalize hormone levels.  Finally melatonin is an antioxidant that protects tissue by neutralizing damaging free radicals.  The amount of melatonin produced by the body naturally declines as we age so supplementing with 5-HTP may be a means to prevent age-related disease.  5-HTP is recommended by natural health practitioners for insomnia, jet lag, aging, cancer, frequent colds and flus, PMS, memory loss, arteriosclerosis, stroke, Alzheimer’s disease, headaches, migraines, obesity, fibromyalgia, stress, anxiety and depression.

5-HTP can be purchased in tablets or capsules.  Taking your supplement with a high-carbohydrate food or drink, like juice, will increase its absorption.

Excessive use of 5-HTP alters the levels of some immune cells.  Regular laboratory testing is recommended.  Do not use 5-HTP if you are pregnant, nursing, have autoimmune disease or cancers of the immune system.  5-HTP interacts with antidepressant medication.  5-HTP has additive effects when taken with St. John’s wort, SAMe and tryptophan.  It may irritate the digestive tract of sensitive individuals.

5-HTP - QUICK FACTS

SOURCES

·  Protein via tryptophan, griffonia plant.

APPLICATIONS

·  Anxiety, depression, fibromyalgia, headaches, migraines, obesity, insomnia, mood support.

OPTIMUM DOSAGE

·   50-300mg daily. (Clinical doses may be higher as recommended by your practitioner).

WORKS WELL WITH

·  Vitamin B6, protein supplements.

IMPORTANT INFORMATION

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·  Excessive use of 5-HTP alters the levels of some immune cells.

·  Do not use 5-HTP if you are pregnant, nursing, have autoimmune disease or cancers of the immune system.

·  5-HTP interacts with antidepressant medication.

·  5-HTP has IMPROVED effects when taken with St. John’s wort, SAMe and tryptophan.

·  Some individuals may get irritation in the digestive tract from using 5-HTP. 

For informational purposes only.  Please consult your health care practitioner before taking natural health care products. Click here for full disclaimer.


All articles copyright National Nutrition 2010 - 2011.  For educational purposes only.  Please note that while National Nutrition supports your right to use natural health care products for any therapeutic purpose that you see fit, that the information on this website should not be considered as a claim or as a substitute for medical advice.

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