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Home > Research Department  > Supplement Articles > NADH / NAD
    Supplement Articles  
NADH /NAD
Articles by a Naturopathic Doctor ( N.D.)

NADH / NAD can assist someone who is feeling sleep deprived and fatigued …

nadh / NAD

Fell more alive and alert during the day
What is it?
Nicotinamide adenine dinucleotide (NADH) is a form of vitamin B3 (niacin) that is also sometimes called coenzyme 1.  Our body can make NADH from dietary niacin or niacinamide. Because of this, deficiency is rare. NADH is necessary for the production of energy inside each of our body's cells.  It also plays a role in the cellular repair of our DNA, the genetic template in each of our cells and in the synthesis of some neurochemicals and hormones involved in brain and mental health.

Energy and Metabolism
It increases the rate of chemical reactions in our mitochondria (the metabolic power plant of our cells) and also helps the cell repair the cellular genetic material (DNA).  Any NADH in the body that is not currently in use for chemical reactions can act as an antioxidant, protecting the cells from damaging free radicals. Free radicals are unstable molecules with an unpaired electron that are extremely reactive, and damage surrounding cell membranes, fats, and fat-soluble vitamins and nutrients. Because of its role in metabolism, NADH is often used for conditions requiring an increase in energy and cellular repair.

Neurologic Effect and Mental Health
NADH also supports the production of certain neurochemicals and hormones in the body, such as adrenaline and dopamine.  Low dopamine levels have been implicated in Parkinson's disease and possibly Alzheimer's disease, so increasing NADH can help to prevent these conditions.  Chronic fatigue syndrome is characterized by low energy, and is also helped by supplemental NADH, perhaps because of increased adrenaline production.  In general, ensuring adequate NADH is a good step towards improving the brain health, and neurochemical balance. Thus, NADH can play a role in improved mental health and brain function.

How can I get more NADH?
This supplement can be found alone in capsules or tablets and is also found in combination formulas for energy enhancements. NADH can be directly supplemented at a dose between 2.5 and 10mg daily. Supplementation of niacin or niacinamide can allow the body to create the amount of NADH it needs naturally.

Important Information
Doses greater than 5mg daily for prolonged periods have been shown to cause insomnia, anxiety, mood-swings and stomach upset. There are no known contraindications reported for the use of NADH.

NADH – QUICK FACTS

SOURCES

· Niacin, niacinamide.

APPLICATIONS

·  Fatigue, Parkinson's disease, Alzheimer's disease, chronic fatigue syndrome.

OPTIMUM DOSAGE

· 2.5-10 mg daily. (Clinical doses may be higher as recommended by your practitioner).

WORKS WELL WITH

·  Niacin, B complex vitamins, vitamin C, vitamin E, selenium, coenzyme Q10.

IMPORTANT INFORMATION

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·  Prolonged use of high doses of NADH (5mg or more) daily have been shown to cause insomnia, anxiety, mood-swings and stomach upset.

For informational purposes only.  Please consult your health care practitioner before taking natural health care products. Click here for full disclaimer.


All articles copyright National Nutrition 2001 - 2012.  For educational purposes only.  Please note that while National Nutrition supports your right to use natural health care products for any therapeutic purpose that you see fit, that the information on this website should not be considered as a claim or as a substitute for medical advice.

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