Lactoferrin-Ultra (Unflavoured) - 1kg

Lactoferrin-Ultra

Lactoferrin Ultra is an exceptional protein formulation based on the latest research. Thanks to its remarkable ability to stimulate the immune system, Lactoferrin Ultra offers new possibilities to patients suffering from immune dysfunction, and infections.

Advanced Whey with Loads of Lactoferrin
Lactoferrin Ultra contains a mixture of whey protein isolate and concentrate high in alpha-lactalbumin to which bovine lactoferrin has been added. The high lactoferrin content is crucial to the effectiveness of Lactoferrin Ultra. Numerous studies have documented that lactoferrin is beneficial for the immune system, that it can prevent infections, and that it is an effective immune boosting agent. Human and bovine lactoferrin share a similar structure, amino acid sequence and biological activity. Recent research has shown that bovine lactoferrin is in fact a more potent inhibitor of certain human viruses.

Lactoferrin with Chemotherapy
Animal studies confirm that the combination of lactoferrin and chemotherapy is more effective than either treatment alone. Lactoferrin can therefore be used to increase the effectiveness of conventional treatments and also to prevent infections. This is a significant advantage because infections secondary to immune dysfunction are a leading cause of mortality in patients receiving radiation or chemotherapy treatments.

Increases Protein Intake
Lactoferrin Ultra contains 89% protein by weight. The ability to maintain adequate nutrition is essential for a favorable prognosis, and proteins are particularly important to prevent the development of cachexia, a condition characterized by weight loss, muscular atrophy, weakness and anorexia.

The health benefits associated with Lactoferr unhealthy cells and prevent the formation of new blood vessels which are needed for unhealthy growth. Lactoferrin has emerged as the most advantageous whey protein component in anticancer research. However, in order to be effective, lactoferrin is needed in large quantities.

A Powerful Antioxidant
Whey protein and lactoferrin are rich in glutathione precursors and studies have shown that they can both effectively increase glutathione levels. Glutathione is an important antioxidant that protects immune cells such as lymphocytes, T cells and NK cells from free radicals. Higher glutathione levels increase the proliferation of immune cells in the spleen. This explains why, in animals, supplementation with whey protein has been demonstrated to reduce the risk of developing colon tumors.

Stimulation of the Immune System
Research has clearly demonstrated that lactoferrin can directly stimulate the immune system. Lactoferrin stimulates the production of cytokines and immune cells, increases IL-18 levels, activates natural killer cells and enhances the cytotoxicity of neutrophils and macrophages. In short, lactoferrin helps to mount an effective immune response. Thanks to its immunostimulating effect, supplemental oral lactoferrin is effective against a broad range of tumors.

Iron Scavenger
The iron scavenging properties of lactoferrin also contribute to its anticancer effect. Free iron is a pro-oxidant and generates free radicals which can damage DNA and cause unhealthy. Lactoferrin binds to free iron, reducing the oxidation load in the body.
Iron is needed for bacterial growth. Lactoferrin sequesters iron, which partly explains its antibacterial activity. Animal studies have clearly demonstrated that lactoferrin reduces bacterial proliferation, preventing bacterial overgrowth in the intestines and reducing bacterial numbers in infected organs. The addition of lactoferrin to the drinking water of animals with fungal infections promotes recovery.

Lactoferrin is also effective against viruses. Other than interferon, lactoferrin is the only agent capable of reducing the presence of the hepatitis C virus in chronic hepatitis C patients. Lactoferrin also has an antiviral effect against human papillomavirus.

A Direct Apoptotic Effect
Lactoferricin is a peptide fraction that is obtained from the digestion of lactoferrin in the stomach. Lactoferricin induces apoptosis directly in several unhealthy cell lines. More specifically, lactoferricin induces apoptosis in human leukemia, lymphoma, breast, colon and unhealthy ovarian cells. It is thought that this induction results from an effect at the level of the mitochondrion.

Lactoferrin Inhibits Angiogenesis
The formation of new blood vessels is required for tumor growth. Lactoferrin is a potent inhibitor of angiogenesis (the formation of new blood vessels) and therefore prevents the progression and spread of tumors. In vitro and animal experiments have demonstrated that lactoferrin prevents angiogenesis, probably through an inhibitory effect on vascular endothelial growth factors (VEG-F).

Alpha-Lactalbumin's Effects
. Lately, alpha-lactalbumin has received some extra attention. A form of alpha-lactalbumin that is unpaired with calcium and then paired with oleic acid (HAMLET, human alpha-lactalbumin made lethal to tumour cells) has been found to have selective and powerful tumoricidal activity. Another study showed that bovine alpha-lactalbumin was just as toxic to tumour cells as the human form. The results of the first human study using HAMLET on patients with unhealthy bladder cells were very encouraging, showing unhealthy cell shedding and tumour size reductions.

Alpha-Lactalbumin
Alpha-lactalbumin has been associated with anti-carcinogenic and anti-microbial activity. In fact, researchers in Sweden conducted a study whereupon a strain of human milk protein consisting largely of alpha-lactalbumin was able to induce apoptosis (programmed cellular death) of unhealthy cells while leaving healthy cells intact. These same researchers have further isolated the co-factors required by the process from which alpha-lactalbumin converts from its native state to the anti-tumourous folding variant now identified as HAMLET (human alpha-lactalbumin made lethal to tumour cells). Furthermore, on a more prevalent level, several clinical studies have determined that bovine alpha-lactalbumin is highly effective at reducing stress. The mechanism of action behind this extraordinary claim is that it raises brain serotonin activity while simultaneously reducing cortisol levels. This opens the potential use of alpha-lactalbumin as a sleep aid, and its cortisol-reducing ability makes it a useful addition to the supplement protocol of anyone dealing with stress. Alpha-lactalbumin has also been studied for its influence on longevity, and in-vivo research among laboratory animals has indicated that it has a dose-dependant effect on life expectancy rates. Furthermore, there has always been a glutathione-enhancing capability attributed to whey protein in general and alpha-lactalbumin in particular. This capability is based on the intracellular conversion (by alpha-lactalbumin) of the amino acid cysteine to glutathione.

A quality whey protein supplement will often consist of about 20% alpha-lactalbumin, and Advanced Whey^TMfrom AOR^TMhas been engineered to consist of more than 36% alpha-lactalbumin.

Lactoferrin
Lactoferrin's prominence in whey protein far exceeds its relatively minute size. In spite of its weight of only 80 kilodaltons at its most elemental level, Lactoferrin contains 703 different amino acids. Lactoferrin is an iron-binding whey fraction that has been known to demonstrate an impressive anti-microbial capability comparable to that of alpha-lactalbumin in addition to being able to control inflammation and cholesterol. Scientists have identified lactoferrin's anti-inflammatory capabilities through its stimulation of the anti-inflammatory cytokines (intracellular messengers) IL-4 and IL-10, and its simultaneous inhibition of the pro-inflammatory TNF-a and IL- cytokines. Lactoferrin's effects on cholesterol levels seem to be based on its ability to reduce the oxidation of LDL cholesterol, an important function considering how oxidized LDL cholesterol can damage artery walls and set the stage for mineral and fat deposits which lead to blockages. Lactoferrin also appears to be the transporter of iron in breast-milk, thus serving as the source of essential amounts of this mineral to nursing infants. Its multifunctional role also encompasses antibacterial, antiviral, antifungal, antioxidant and immunomodulatory activities.

Lactoferrin's multi-faceted applications make any single mechanism of action challenging for scientists to isolate, but most seem to agree that it begins with lactoferrin's ability to bind to iron. Iron is essential for the growth of pathogenic bacteria and is also a major contributor to the generation of reactive oxygen species. This would go a considerable distance towards explaining the anti-microbial, antioxidant, anti-inflammatory and immunomodulatory activities of lactoferrin. Lactoferrin forms a much smaller percentage of whey protein than does alpha-lactalbumin.