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Home > Research Department  > Supplement Articles > Pantethine
    Supplement Articles  
PANTETHINE
Articles by a Naturopathic Doctor ( N.D.)

Pantethine is a form of Pantethenic acid (vitamin B5). It has been found to be the more biologically active form of B5, although considered somewhat less stable ...

Pantethine serves as a precursor for the synthesis of coenzyme A, which is one of, if not the most biologically involved metabolic enzymes in the human body. It is essential for the process of fatty acid degradation. As such, it plays a significant role in regulating cholesterol levels.

PANTETHINE

Pantethine for lowering LDL and total cholesterol.

Studies have shown pantethine is effective in lowering both LDL and total cholesterol, as well as triglycerides, an effect that the related Pantethenic Acid form cannot demonstrate. Coenzyme A is also necessary for the production of a variety of hormones and neurotransmitters, as well as activation of white blood cells for immune support.

Pantethine, being integral in the production of Coenzyme A, can help to combat stress and is often found in combination with herbs to be used as an adrenal support. The exact mechanism as to how pantethine exerts these effects is still unclear. Pantethine deficiency may cause a severe decrease in energy and poor nervous system functioning.

Pantethine is found in mushrooms, avocados, eggs and lentils, or can be taken in supplement form.

Be sure to look for a supplement showing pantethine and not pantethenic acid, as this acid form does not have the same cholesterol lowering effects.

For stress relief and overall health, a dosage of 100-300 mg/day is adequate. To achieve the cholesterol lowering effects of pantethine, dosages between 600-1200 mg/day are recommended.

PANTETHINE – QUICK FACTS

FOOD SOURCES

·  Mushrooms, avocados, eggs, lentils, fish, organ meats, whole grains, yogurt.

APPLICATIONS

· High cholesterol/hyperlipidemia, immune support, stress/adrenal fatigue.

OPTIMUM DOSAGE

· Depending on the condition, anywhere from 100-1200 mg/day in divided doses has been shown safe.

WORKS WELL WITH

· Fibre, CoQ10, Hawthorn, other B vitamins (B-complex).

IMPORTANT INFORMATION

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· Pantethine may increase bleeding time if you are already on an anti-coagulant medication, or natural blood thinning agent, consult your healthcare professional.

For informational purposes only.  Please consult your health care practitioner before taking natural health care products. Click here for full disclaimer.

All articles copyright National Nutrition 2001 - 2011.  For educational purposes only.  Please note that while National Nutrition supports your right to use natural health care products for any therapeutic purpose that you see fit, that the information on this website should not be considered as a claim or as a substitute for medical advice.

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