All of these effects leading to decreased risk of atherosclerosis and stroke. It has also been shown to reduce c reactive protein levels, a marker of inflammation, often high in cardiovascular related pathologies.

Safflower and weight loss
People are paying attention to Safflower in regards to its weight loss effects. Although more research is needed, it seems that safflower oil may help reduce weight in postmenopausal women who are already obese or overweight and suffering from diabetes, or are prediabetic. Studies have shown that in cases of metabolic syndrome, supplementing with safflower oil has been shown to reduce weight and fasting glucose levels, and mildly decrease HbA1C levels in the blood (a marker of long-term blood sugar status) while also increasing insulin sensitivity. Safflower oil is high in linoleic acid, studied in isolation for its weight loss effects. CLA has been shown to reduce both body fat mass, as well as measures of sagital abdominal diameter. Abdominal obesity has been strongly linked to metabolic syndrome.

Everything in moderation: maintaining a healthy ratio of Omega 6: Omega 3 fatty acids
Although safflower oil is an amazing source of omega 6 fatty acids, it is necessary to maintain an equally high intake of Omega 3 fatty acids. Nowadays, we are averaging about 10-30:1 of Omega 6: Omega 3 fatty acids in our diet. We want to aim for a 2:1 ratio. Omega 6 fatty acids do have a greater propensity to create inflammatory compounds (as opposed to omega 3's which create anti-inflammatory substances). Furthermore, Omega 6 fatty acids and omega 3 fatty acids utilize the same enzymes and transport systems, meaning they compete. If the ratio of omega 6:omega 3 fats is 20:1, there is very little raw material left for omega 3's to create and exert their anti-inflammatory benefits.

Quality matters
Look for a high quality organic, RAW safflower oil, if using it as a supplement. Many of the processes used to refine safflower oil, along with a number of omega 6 fatty acids, strip the oil of its nutrients.

More details, please! - Dosage and safety information
There is no known therapeutic dosage for safflower oil. Safflower oil can be purchased at your local grocery store, although make sure to bring your reading glasses, as it is important to stay away from highly refined or processed oils. Again, look for organic, raw or even cold pressed varieties. Safflower oil can also be purchased in supplement form, usually in liquid or softgel. Do not take in therapeutic amounts during pregnancy or while breastfeeding. Safflower may cause uterine contractions. Safflower may cause allergic reaction in those with a ragweed allergy. Safflower does have mild blood thinning effects. When using as medicine, be sure to stop using about 2 weeks prior to scheduled surgery and speak with your Naturopath or doctor before using if you have a bleeding disorder.