NOx (Nitric Oxide) Supplements
How Does Nitric Oxide Support Circulation?
Nitric oxide (NO) is a fascinating molecule with a wide range of physiological and biochemical functions. It is a colourless, odourless gas synthesized from the amino acid L-arginine in a reaction catalyzed by the enzyme nitric oxide synthase (NOS). Nitric oxide is a highly reactive molecule, and its discovery in the late 20th century revolutionized our understanding of vascular biology and has had far-reaching implications for medicine and physiology. Read more >-
Naturopathic Labs NOSx Nitric Oxide Booster is a thoughtfully formulated performance supplement featuring L-Citrulline, L-Arginine, and organic beetroot. Designed to support nitric oxide production, it helps promote healthy circulation and endurance during your workouts. This blend also provides antioxidants to help protect cells from everyday oxidative stress, along with amino acids that play ...
+ Earn 12 Reward PointsSale: $12.99
Reg.: $15.99 (Save $3.00)
In Stock -
Naturopathic Labs NOSx Nitric Oxide Booster is a thoughtfully formulated performance supplement featuring L-Citrulline, L-Arginine, and organic beetroot. Designed to support nitric oxide production, it helps promote healthy circulation and endurance during your workouts. This blend also provides antioxidants to help protect cells from everyday oxidative stress, along with amino acids that play ...
+ Earn 19 Reward PointsSale: $19.99
Reg.: $24.99 (Save $5.00)
In Stock(Click Add to Select Bonus)
-
Naturopathic Labs NOSx Nitric Oxide Booster is a thoughtfully formulated performance supplement featuring L-Citrulline, L-Arginine, and organic beetroot. Designed to support nitric oxide production, it helps promote healthy circulation and endurance during your workouts. This blend also provides antioxidants to help protect cells from everyday oxidative stress, along with amino acids that play ...
+ Earn 29 Reward PointsSale: $29.99
Reg.: $44.99 (Save $15.00)
In Stock(Click Add to Select Bonus)
-
Are you eager to discover your body’s full capabilities? Bucked Up’s Pump-ocalypse is a blend nitric oxide boosters that not only promotes your body’s power output, but also helps boosts blood circulation to your vessels, aiding your other supplements (such as pre-workout and BCAAs) to be absorbed more effectively and perform as intended. In essence, Pump-ocalypse unleashes both your body’s pot...
+ Earn 69 Reward PointsOur Price: $69.99In Stock -
Designs For Health's NOx Synergy is a carefully crafted formula aimed at enhancing nitric oxide (NO) levels within the body. Nitric oxide is a small yet crucial molecule that facilitates the relaxation of blood vessels, thereby promoting healthy blood circulation throughout the body. This function is particularly essential for supporting muscle contraction and endurance both during and after ph...
+ Earn 124 Reward PointsOur Price: $124.78In Stock -
HumanN Neo40 Daily is a breakthrough formula helps your body naturally increase Nitric Oxide levels, thus helping improve circulation, supporting the cardiovascular system and improving performance in adults over the age of 40. Neo40 Daily has been shown to reduce important cardiovascular risk factors, such as inflammation, triglycerides - even C-reactive protein levels - one of the most reliab...
+ Earn 49 Reward PointsSale: $49.99
Reg.: $64.99 (Save $15.00)
In Stock(Click Add to Select Bonus)
-
Naka Platinum NOx is an advanced workout and performance supplement formulated with L-Citrulline, L-Arginine, and Organic Beetroot to help support nitric oxide production and optimize athletic performance. It serves as a source of antioxidants that help protect cells from damage caused by free radicals, while also providing non-essential amino acids involved in muscle protein synthesis. When co...
+ Earn 22 Reward PointsSale: $22.99
Reg.: $32.99 (Save $10.00)
In Stock(Click Add to Select Bonus)
-
Naka Platinum NOx is an advanced workout and performance supplement formulated with L-Citrulline, L-Arginine, and Organic Beetroot to help support nitric oxide production and optimize athletic performance. It serves as a source of antioxidants that help protect cells from damage caused by free radicals, while also providing non-essential amino acids involved in muscle protein synthesis. When co...
+ Earn 32 Reward PointsSale: $32.99
Reg.: $34.99 (Save $2.00)
In Stock -
Natra’s NITROpro is a well-rounded formula designed to support circulation, energy, and overall performance. It combines beetroot extract, amino acids, and adaptogens to help your body efficiently deliver oxygen and nutrients to working muscles. Ingredients like L-arginine and L-citrulline support healthy blood flow, while beta-alanine and HMB help maintain endurance and muscle balance. L-thean...
+ Earn 39 Reward PointsOur Price: $39.98In Stock -
NITROfit Fro Women from Natra is a targeted formula designed to support circulation, energy, and performance during physical activity. It combines amino acids like L-arginine and L-citrulline with beetroot to help support healthy blood flow and nutrient delivery. Beta-alanine and HMB help maintain endurance and muscle balance, while L-theanine promotes calm focus. Created with women in mind, th...
+ Earn 39 Reward PointsOur Price: $39.98In Stock -
1000MG L-ARGININE FREE FORM AMINO ACID FROM NOW FOODS. This double strength free form amino, L-Arginine plays an important role in vascular health, immune function, growth hormone production and more. Providing a maximum 1000mg dosage per cap Now's L-Arginine looking potent support. L-Arginine is needed by the body to synthesize nitric acid, which in turn helps arterial walls relax allowing bl...
+ Earn 24 Reward PointsSale: $24.99
Reg.: $32.99 (Save $8.00)
In Stock -
500MG ACTIVE ARGININE in the superior "L" form. Arginine is considered an essential amino acid, which means that our bodies can not naturally produce it. However studies show that, for some individual's supplementation may offer an array of health benefits. Derived from natural sources, Now's arginine amino acid is free of binders and fillers and is suitable for many different clinical applica...
+ Earn 12 Reward PointsSale: $12.99
Reg.: $17.99 (Save $5.00)
In Stock -
100% PURE-FREE FORM L-ARGININE POWDER FROM NOW FOODS. L-Arginine plays an important role in vascular health, immune function, growth hormone production and more. Now's L-Arginine powder is easily absorbed providing 4.6g (2 teaspoons). L-Arginine is needed by the body to synthesize nitric acid, which in turn helps arterial walls relax allowing blood to flow easily throughout the body. L-Arginin...
+ Earn 39 Reward PointsSale: $39.99
Reg.: $49.99 (Save $10.00)
In Stock -
500 MG L-ARGININE FROM NEW ROOTS HERBAL Considered an essential amino acid, L-Arginine has a number of important functions in the body. Research suggests supplementation may be useful for those concerned with weight loss and muscle gain; immune function and growth hormone production. It also has shown to be helpful to men concerned with sterility. New Roots herbal provides 500 mg of l-arginin...
+ Earn 36 Reward PointsSale: $18.79
Reg.: $21.29 (Save $2.50)
In Stock -
500MG ACTIVE ARGININE in the superior "L" form. Arginine is considered an essential amino acid, which means that our bodies can not naturally produce it. However studies show that, for some individual's supplementation may offer an array of health benefits. Derived from natural sources, Now's arginine amino acid is free of binders and fillers and is suitable for many different clinical applica...
+ Earn 24 Reward PointsSale: $24.99
Reg.: $29.99 (Save $5.00)
In Stock(Click Add to Select Bonus)
Nitric Oxide Supplements & Circulation
Nitric oxide (NO) is a fascinating molecule with a wide range of physiological and biochemical functions. It is a colourless, odourless gas synthesized from the amino acid L-arginine in a reaction catalyzed by the enzyme nitric oxide synthase (NOS). Nitric oxide is a highly reactive molecule, and its discovery in the late 20th century revolutionized our understanding of vascular biology and has had far-reaching implications for medicine and physiology. Nitric oxide and nitric oxide supplements are known to support your health in many ways including heart and circulatory health.
How Your Body Makes NO
The body's most well-known source of nitric oxide is the endothelium, which is the inner lining of blood vessels. Endothelial cells produce nitric oxide in response to various stimuli, including shear stress from blood flow, acetylcholine, and certain hormones. This endothelial NO helps regulate blood vessel tone and dilates blood vessels, thus increasing blood flow. This function is vital for maintaining healthy blood pressure and ensuring proper blood supply to tissues.
Neurons in the central and peripheral nervous systems also produce NO – known as neuronal nitric oxide, which functions as a neurotransmitter, aiding in the transmission of signals between nerve cells. In the brain, nitric oxide plays a role in memory formation, learning, and other cognitive functions.
In addition, immune cells, such as macrophages and neutrophils, can produce NO in response to infection and inflammation. This type of nitric oxide, known as inducible NO, helps the immune system combat pathogens.
However, if your body doesn't produce adequate amounts of nitric oxide on its own, supplements may be beneficial.
Various Nitric Oxide Supplements - Potencies, Forms & Formats
Nitric oxide is widely available in supplement form, typically sourced from the amino acid L-arginine or its precursor, L-citrulline. L-arginine can be converted into nitric oxide through synthesis when ingested. On the other hand, L-citrulline can indirectly boost nitric oxide production by being converted into L-arginine within the body, providing a sustained source for nitric oxide synthesis. NO, once produced, plays a crucial role in dilating blood vessels, improving blood flow, and supporting various physiological functions, making it a popular dietary supplement for enhancing cardiovascular health and exercise performance.
Nitric oxide supplements come in various forms, including capsules, powders, and liquids. Typical dosages vary depending on the product and individual needs but range between 1,000 to 3,000 mg (of L-arginine, L-citrulline, or a combination of both), taken 30 minutes to an hour before exercise. If you're using NO for overall cardiovascular health or other reasons other than exercise, it's recommended to take it before meals.
Key Benefits of NO Supplements On Your Health
- Vasodilation – Nitric oxide supplements are a potent vasodilator that relaxes and widens blood vessels. This vasodilatory effect helps regulate blood pressure by reducing resistance to blood flow. Dysfunctional nitric oxide production can lead to conditions like hypertension.
- Neurotransmission – NO functions as a neurotransmitter in the nervous system, facilitating communication between neurons. It is involved in memory, learning, and synaptic plasticity processes.
- Immune Response – Nitric oxide produced by immune cells is part of the body's defence against pathogens. It acts as a cytotoxic agent, helping to destroy bacteria, viruses, and other microorganisms.
- Platelet Function – NO inhibits platelet aggregation, which prevents blood clot formation and helps maintain proper blood flow.
- Anti-inflammatory Effects – Nitric oxide has anti-inflammatory properties and can help modulate the body's immune response to reduce tissue damage during inflammation.
- Erectile Function – In the male reproductive system, NO plays a vital role in the relaxation of smooth muscle in the blood vessels of the penis. This allows for increased blood flow, leading to erections. Medications like Viagra work by enhancing the effects of nitric oxide.
- Cell Signaling – Nitric oxide is a signalling molecule in various cellular processes, influencing gene expression, cell growth, and differentiation.
- Oxygen Transport – In the lungs, nitric oxide binds to hemoglobin, increasing its affinity for oxygen and improving oxygen transport in the bloodstream.
Who Would Benefit From Nitric Oxide Supplements?
NO supplements can be beneficial for a wide range of individuals. Athletes and fitness enthusiasts often use these supplements to enhance their exercise performance and endurance, as nitric oxide helps dilate blood vessels, increasing blood flow to muscles. This improved circulation can also benefit those with cardiovascular conditions, aiding in the management of blood pressure and overall heart health. Additionally, individuals seeking cognitive enhancement may find nitric oxide supplements appealing, as they promote better blood flow to the brain, which can improve cognitive function, especially in those with cognitive impairment and various forms of dementia. Furthermore, those looking to address erectile dysfunction may find nitric oxide's role in vasodilation helpful for improving blood flow to the genital area.
Things To Consider When Using Nitric Oxide
While generally well tolerated, some individuals may experience headaches, dizziness, or nausea when taking nitric oxide. In such instances, reduce dosage or discontinue use. Additionally, nitric oxide should be used with caution in those with certain underlying medical conditions, such as chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis, as it may worsen their respiratory symptoms.
Back to Top ↑
