Aging & Anti-Aging Supplements
Updated Jul. 08th, 2026 | Read Time: 6 Minutes | What You Will Learn:
- What Is Aging?
- Physical Aging
- Telomere Shortening
- Causes of Aging
- Free Radical Damage
- Hormone Loss
- Lifestyle Changes & Supplements For Anti-Aging
- Dietary Changes
- Lifestyle Changes
- Liver Support
- Digestive Support
- Anti-Aging Supplement Varieties
- Antioxidants
- Resveratrol
- Astragalus
- Carnosine
- Coenzyme Q10
- Carotenoids
- Nutritional Information
- Reader Comments (23)
Aging describes the physical changes that accumulate in the body over time. It commonly refers to age-related declines in health. Aging also causes psychological and social changes. However, this article focuses on physical aging. Since the time of the industrial revolution, human longevity has been increasing. The most common causes of death are no longer communicable diseases but are instead diseases from lifestyle and environmental sources. Maintaining a healthy body remains a key focus of anti-aging strategies. Anti-aging supplements and lifestyle changes may support this goal.
What Is Aging?
Physical Aging
Physical aging does not always match chronological age. People of the same age can age differently. Scientists call the physical aging of cells and the body senescence. Senescence describes the gradual loss of cellular stress response and metabolic balance. When enough stressors happen, the cell cannot respond well enough and will succumb and die. Our ability to resist these stressors and replace these dying cells is the key to staying young. Cell division supports health by renewing skin, blood, bone, and other essential cells.
Telomere Shortening
Researchers link cellular senescence in humans to shortened telomeres at chromosome ends. Telomeres protect DNA during replication, similar to plastic tips protecting shoelaces. Each cell division shortens telomeres slightly. Eventually, cells lose regenerative ability, contributing to aging. Scientists consider telomeres a molecular clock for cell lifespan. Telomere shortening isn't all-bad though, it acts as a protective failsafe against the formation of cancer. In fact, 85% of cancers contain a mutation that activates an enzyme (telomerase) that repairs the telomeres of the cell and prevents shortening.
What Are The Causes of Aging?
Free Radical Damage
The number one cause of damage to our cells is exposure to free radicals. Free radicals are unstable molecules with an unpaired electron that are extremely reactive, and damage surrounding cell membranes, fats, and fat-soluble vitamins and nutrients. We encounter free radicals through environmental exposures, such as cigarette smoke, air pollution, processed foods, and ultraviolet radiation from the sun (UV rays).
The damage caused by free radicals can cause cell death, alterations in genetic material and autoimmune reactions to damaged cells. Because of this, it is important to reduce your exposure to these damaging substances by using natural products and avoiding environmental exposures. To help neutralize the effects of those free radicals that you cannot avoid, ensure your diet is rich in as many antioxidants as possible.
Hormone Loss
Aging inevitably results in a decline in the production of our sex hormones over time. These hormones play essential roles in maintaining muscle mass and bone density, as well as many other health markers. Men experience andropauce when natural testosterone production declines.
Lifestyle Changes & Supplements For Anti-Aging
Dietary Changes
Research in mice has shown that when they are fed a diet that contains 30-50% less calories than an unrestricted diet, but still contains all the nutritional requirements, it can lead to an increase in lifespan of up to 50%. Calorie restriction may delay cardiovascular disease, diabetes, and unhealthy cell growth. The easiest way to do this is to focus your diet on fruits and vegetables rich in vitamins and nutrients.
Lifestyle Changes
Lifestyle changes can significantly improve quality of life and longevity. Gaining healthy habits such as regular exercise, good quality sleep, breathing exercises, and a clean diet, as well as dropping unhealthy activities such as smoking and chemical exposure, will increase vitality. Internally, as we age, we lose muscle mass (sarcopenia), so by doing weight-bearing exercise, you can delay muscle degradation. All exercise will aid in increasing telomerase activity, which helps enhance and elongate the life of our cells. You can support aging skin by moisturizing with creams containing natural oils like avocado, almond, and olive oil. To avoid damaging your skin, limit sun exposure, be sure to use sunscreen (which will minimize age spots) and avoid direct contact with harsh, cleansing chemicals.
Liver Support
Because our liver is the organ responsible for detoxifying our body and for eliminating most reactive substances like free radicals from the body, it is essential that we support its health and function. Some substances that do this are: N-Acetyl Cysteine (NAC), milk thistle, B complex vitamins, and D-glucarate.
In addition to support your liver, after a time of toxic buildup, such as holidays or celebrations, it is often a good idea to do a liver and kidney detox to help clear out any extra toxic build up you may have accumulated, and to ensure those elimination pathways are running smoothly.
Digestive Support
Much like the liver, your digestive tract is the key to your ability to eliminate a large amount of your toxic burden. It is the most direct way for waste to leave our body, and it is where the liver releases the toxins that it has processed. Because of this, healthy digestion is one of the keys to aging well.
Anti-Aging Supplement Varieties
Antioxidants
Most fruits and vegetables naturally contain a variety of antioxidants, especially berries such as: blueberries, acai, goji, noni, and other super fruits. Many vitamins also act as antioxidants in the body. These make for great anti-aging supplements; they include vitamin A, C, E, CoQ10, and carotenoids.
Resveratrol Supplements For Anti-Aging
This nutrient appears in many common foods:
- Red wine
- Berries
- Skins of other brightly coloured fruits
Studies examining resveratrol showed dramatic results for reducing the incidence of unhealthy cell growth by acting directly on these cells to cause their death. Resveratrol can also protect the heart and cardiovascular system by maintaining the integrity of artery walls and by reducing the thickness of the blood.
Astragalus
Research shows astragalus root compounds may increase telomerase activity. Some companies market these supplements for anti-aging support.
Carnosine
This small protein subunit may support mental function and provide antioxidant protection against cellular damage.
Coenzyme Q10 Supplements For Anti-Aging
One of the natural enzymes in the body, commonly known as CoQ10, is an extremely strong antioxidant that can help to prevent the physical signs of aging. This nutrient also helps create ATP, the body's primary energy molecule.
Carotenoids
Often, anti-aging skincare products contain a type of natural antioxidant compound extracted from yellow or red fruits and vegetables. Researchers call these compounds carotenoids.




The health benefits to fight aging, as mentioned under dietary changes box, regarding the mice was due to autophagy state. where the body falls into a repair and create new cells. esentially leading up to a healthy skin and bone feeling and fat loss status. I personally have done that 72 hour fast twice and feel great afterwards because of the nutrients and vitamins I get from national nutrition (vcaps). Autophagy is the new science that helps reduce the aging process and reverse in some cases. Fasting and exercise both promote this autophagy phenomenon so please look into that, there are many medical journals and studies that all support the anti-aging benefit of it. Of course make sure you see a practitioner before doing any extreme fasts to make sure it doesn't conflict with any current medical conditions you have.
I think it is best to get as much as you can out of your food before taking a supplement. For example, eat a small bowl of blueberries every morning with you cereal. Have a handful of almonds or other nuts as a snack instead of chips. Have a fruit after each meal before you eat dessert. Every little bit helps.
Loved this read. Very informative for how to age gracefully with natural supplements and products.
Hello Barb,
We're glad you enjoyed our article on Aging and have learned how to care for your changing health naturally! Here are some articles on supplements that go well through all seasons of life:
https://www.nationalnutrition.ca/articles/supplements/collagen-1-and-3/
https://www.nationalnutrition.ca/articles/supplements/collagen-2/
Stay healthy & well!
Excellent article on anti aging and the benefits of targeted supplementation. I often tell people that you can't stop the process but you can certainly delay it by incorporating a healthy lifestyle including exercise, proper diet, stress management and supplementation. I was surprised that the Japanese 'knotweed' wasn't mentioned as the primary resveratrol source containing 'emodin.'
Hello Marco,
Thank you for your comment and we are glad you're enjoying our articles. Anti aging can be supported through many lifestyle choices. Here's our article on other things to consider for skin health too:
https://www.nationalnutrition.ca/articles/health-concerns/skin-health/
Stay healthy & well!
In addition to the tips listed above, I would also like to add that intermittent fasting, drinking matcha tea and bone broth helped me noticeably improve my skin. My method of fasting is eating 2 meals per day six days a week and then eating only 1 meal 1 day per week. I have more energy, my digestion is better, and allergy symptoms are improving just by fasting. The improved skin and hair is a bonus to me.
Hello Hassan,
Thank you for sharing your tips and experience. If you'd like to learn more about matcha, don't forget to check out our supplement articles too:
https://www.nationalnutrition.ca/articles/supplements/matcha/
Stay well!
I have to say aging for me is very scary and as I get older and see more changes to my body and appearance and the way I feel, I get worried. It's scary to know that something is inevitable and it is useful and calming to know that there are things that one can do to slow the process a bit. This article has made the notion of aging a bit less scary for me and it identifies key things that can be done to age gracefully and puts things in perspective for me.
Hello,
Thank you for sharing. We are happy to hear that our articles not only help you learn about natural health but also ease any anxieties you may have. Being proactive about your health can certainly help keep you feeling and looking vivacious and energetic. We think you'll enjoy learning some skin health tips from this article as well:
https://www.nationalnutrition.ca/articles/health-concerns/skin-health-aging/
Have a healthy day!
Great article, love the examples given of the food items we can use to benefit aging, will try them out!
Hello Dav,
Thank you for your feedback, we're glad you enjoyed reading about how nutrition can help with anti aging. Food or supplements rich in antioxidants are definitely important when looking to maintain youthful and supple skin and a healthy inside as well. You can learn more about the power of antioxidants here, https://www.nationalnutrition.ca/articles/supplements/antioxidants/
Have a healthy day
This article was very informative, I learned a lot and I especially liked that they provided supplement and dosage information to prevent sign of aging.
Hello Jennifer,
Thank you for your comment, it's nice to hear how much you enjoyed our article on anti-aging. You can discover more about the nutrients outlined in this article by exploring our supplement articles: https://www.nationalnutrition.ca/articles/supplements/
Stay well
This article "Aging (Anti-Aging)" is a thorough and informative resource for anyone interested in understanding the science of aging and the various strategies available to combat its effects. Its combination of scientific insights, practical advice, and balanced discussion makes it a valuable read for those looking to adopt a healthier lifestyle and explore the potential of anti-aging treatments. Despite some minor areas for improvement, the article stands out as a comprehensive guide to navigating the complex and rapidly evolving field of anti-aging.
Hello,
Thank you for your comment, we're thrilled you enjoyed learning natural ways to combat aging both inside and out. We're glad you enjoyed our article.
Have a healthy day.
Meditation is also great way for anti-aging, as well as sleep well.
Hello Ning,
Yes, meditation and quality sleep will help decrease stress and signs of aging both internally and externally. Thank you for sharing.
I am not that old yet but I can feel the aging process working inside me. I already take many of these supplements, but it is a long, slow process to see real changes. I feel the products working inside. I like combining supplements with getting enough sunshine, especially in Canada during winter. It's so important to take Vitamin D drops, it's a lifesaver when there is only one or two sunny days per month. Thanks for confirming which supplements are needed to stay young.
Hello Kaveh,
It's great to know the nutrients that help you age gracefully because skin aging is something that's better to be proactive about rather than trying to reverse it. We're glad you enjoyed this article, you can learn more about ways to take care of your skin here: https://www.nationalnutrition.ca/articles/health-concerns/toxic-skin-care-ingredients/
As an MIT graduate in biology as well as a current PhD student at UCSF in the biology department, I give you applause for in an article for the public clearly explaining biological concepts including telomeric shortening contributions to the aging process in addition to free radicle damage contribition to the aging process. Also, I think that some of the supplement suggestions are really awesome :D I love green tea for all the antioxidants and all the other health benefits. Vitamin D is also awesome (and essential for anyone who is using sunscreen for aniaging skin benefit!)
Hello Rachel,
Happy you enjoyed how in depth this anti aging article goes. It's important to take care of your body from the inside out to combat the effects of aging. Be sure to read through this article on toxic ingredients to avoid: https://www.nationalnutrition.ca/articles/health-concerns/toxic-skin-care-ingredients/
WOW There are so many things that are related to aging and I never would have knew it all or knew most of it if I had not stumbled upon your website. This is great and I want to know more.
I love that it is such a lively discussion section also and I think Bo Arabzadeh has an insightful comment on practically trying to get autophagy to work in his/her own life and I agree with Elisa that I try to get things I need a lot from food so something like blueberries in the morning can be very helpful. That said supplements can definitely still be useful here as the aging body can get worse at doing healthy things with healthy foods so I will read your pages on it-THANK YOU!!