Gla - 240 - 90 Softgels - Aor

Gla - 240 - 90 Softgels - Aor

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product description:
GAMMA LINOLENIC ACID (GLA) FROM AOR.GLA-240 is gamma-linolenic acid (GLA), an "activated" fatty acid found in evening primrose oil and in more concentrated form in borage oil. Extensive scientific research shows that GLA supplementation favorably modulates the body's balance of eicosanoids, local cellular "hormones" which regulate inflammation, thrombosis (abnormal blood clotting), and immune function. Eicosanoid imbalances are involved in many of the symptoms of menopause and premenstrual syndrome (PMS). [SOFTGELS]
1 softgel contains:
240 mg
Gamma linolenic acid (GLA) (from 100% borage oil)
5 IU
Vitamin E (D-Alpha tocopherol)
Other ingredients:
ascorbyl palmitate.

Softgel:
gelatin and water.

Format

format thumbSoftgels

90 Softgels

Dosage

Take one softgel daily with a fat-containing meal, or as directed by a qualified health consultant.

Important Information

Free of all common allergens, including: no wheat, gluten, corn, nuts, dairy, soy, eggs, fish or shellfish.

Highlights
  • Inflammation, swelling and pain.
  • Pressure in joints, blood vessels.
  • Water retention.
  • Allergic response.
  • Rheumatoid arthritis.
  • Nerve transmission.
  • Pre-menstrual syndrome.
  • Vascular disorders.

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Articles by a naturopathic doctor.

Manufacturer Info

AOR Canada is the innovative formulators of Canada’s best-selling antioxidant support, AOR Advanced B Complex and AOR Tri-B12. They are also known for their top bone health supplements, Ortho Adapt and Bone Basics. You can also SHOP AOR's Nattokinase, and trusted Curcumin Ultra, Curcumin Active and Curcumin95 inflammation support at National Nutrition.ca. AOR are leaders in natural health with innovative product development.

How Everyone Can Benefit From Adding GLA to their Diets

Borage is a plant with star shaped, periwinkle-blue flowers. The plant produces a dark, rich oil that contains valuable therapeutic lipids. The seed pod usually contains about 25% oil content.

The body is capable of naturally producing GLA. In order to do this, it must have its starting material, linoleic acid (LA). This is an essential fatty acid that the body is unable to make and must be ingested as part of the everyday diet. Fortunately, most people get plenty of LA in their daily diet, since it is commonly found in almost all edible vegetable oils.
Once LA is ingested, it is acted upon by an enzyme called delta-6-desaturase (D6D) which biochemically converts LA to GLA. This is how the body gets its daily fix of GLA.
Without the effective functioning of D6D, the body is unable to manufacture any GLA no matter how much LA is ingested. GLA is further converted via a sequence of biochemical steps into prostaglandin 1 (PGE1), a key molecule with numerous biological properties including:

  • Anti-inflammatory.

  • Dermatology (e.g. eczema).

  • Anti-allergy.

  • Nerve transmission.

  • Secretion from the mucus membrane.

  • PMS.

  • Steroid production and hormone synthesis.


  • The first vegetable source of GLA was discovered in the oil of evening primrose seeds (where GLA content is 9%). This oil became well known with the public, health professionals, and in health stores. Then GLA was also discovered in borage and black current in higher amounts, 24% and 17% respectively. A 1992 study published in the journal 'Lipids' showed that "there was no significant difference in tissue GLA levels within groups given equal amounts of dietary GLA either in borage oil or evening primrose oil". In order to ingest 240mg of GLA, only 1 000mg of 24% borage oil needs to be taken compared to 2 660mg of EPO. Because reduced consumption of oil is desirable as a rule, the higher GLA potency of borage oil makes it preferable to evening primrose oil.

    Clinical Studies

    Anti-inflammatory
    In rheumatoid arthritis (RA), benefit from non-steroidal anti-inflammatory drugs (NSAIDs) is mediated through inhibition of the cyclo-oxygenase enzyme, thereby decreasing production of the 2 series prostaglandins (PG2). The Lipoxygenase enzyme is intact, however, allowing leukotriene (LT) production; e.g. LTB4 is an inflammatory mediator. Treatment with GLA-240 leads to the production of the prostaglandin 1 series PGE1, which has less inflammatory effects. In addition, LT production is inhibited.

    Post-viral fatigue syndrome
    63 adult patients were treated with GLA for 3 months in a double-blind, placebo-controlled study. All patients had been ill for 1-3 years of a viral infection and were suffering from myalgia, severe fatigue and a variety of psychiatric symptoms. The essential fatty acid composition of the red cell membrane phospholipid improved significantly.

    Mastalgia
    414 patients with mastalgia were treated with Danazol, bromocriptine, or GLA. Danazol was the most effective, with GLA and bromocriptine having equivalent efficacy. However, many more adverse effects were noted with danazol and bromocriptine.

    Diabetic neuropathy
    A 1 year study observed 111 patients with mild diabetic neuropathy who were treated with 480mg of GLA per day and assessed for 16 parameters including tendon reflexes, muscle strength, hot and cold sensation etc. For all parameters, the changes were more favorable and statistically significant in the GLA group. The conclusion was that GLA had beneficial effects on the course of diabetic neuropathy.

    Cautions


  • Possible interactions with phenothiazines (increasing seizure risk).


  • May cause headaches and/or nausea.


  • May increase bleeding time.
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