- 500mg
- Quercetin (3,3', 4', 5,7-Pentahydroxyflavone)
Keep out of reach of pets & children. Consult with a health care practitioner if breast feeding or pregnant. Contains no added gluten, eggs, animal products, dairy products, fish or shellfish, soy, corn, wheat or yeast.
Veggie Caps
240 V-caps
Adults: Take 1 capsule two times/day. Take with meal.
- Helpful for seasonal allergies
- Helps maintain a balanced immune response
- May also enhance digestion when taken with meals
- Supports Free Radical Damage
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What is Quercetin?
Quercetin is a flavonoid, a class of antioxidants commonly found in fruits. Its use has been widely established particularly in Europe, for the treatment of a variety of ailments. Quercetin decreases the formation and activity of inflammation mediators in a manner that is similar to that of aspirin. An important function considering these inflammatory intracellular messengers is what cause the body's pain receptors to become more sensitive.
Quercetin also inhibits the release of histamine by stabilizing the cellular membranes of neutraphils, which are a type of immune cell. Quercetin is therefore widely used by those who suffer from constant allergies (such as dust) and seasonal allergies (such as hay fever).
In a study investigating the risk factors for chronic diseases in elderly men, it was revealed that high intakes of quercetin and other flavonoids predicted lower mortality rates and incidences of a heart attack. Researchers in the Netherlands believe it is possible that quercetin and other flavonoids, reduce the risk of heart disease by lowering the formation of plaque-building substances, specifically oxidized low-density lipoprotein (LDL).
Benefits Of Quercetin Supplements
As reported by the literature:
- Cardiovascular system.
- Circulation.
- Analgesic properties.
- Antioxidant.
- Hyperglycemia.
- Allergies.
An Antioxidant Flavonoid
antioxidants stop oxidants (free radicals, which disrupt the integrity of other molecules by stripping their electrons) from attacking nearby molecules, such as mitochondria, membranes, and DNA. There are many classes of dietary antioxidants, and flavonoids are one of them. Flavonoids have many phenols linked to their antioxidants.
Common sources of flavonoids are vegetables, fruits, and beverages such as wine and teas. Of the many flavonoid powerhouses, Quercetin is a major player. Quercetin is the most widely consumed flavonoid in the diet. Quercetin has been widely used by Russians and Europeans to treat a variety of ailments.
Mechanism Of Action
Pain and Inflammation
Natural quercetin supplements decrease the production of inflammatory mediators by inhibiting key enzymes called cyclooxygenases and lipoxygenase, which form proinflammatory eicosanoids (local microhormones) such as PGE2 and PGE2 alpha. The mechanism is similar to that of aspirin and indomethacin. Mediators such as histamine, bradykinin and PGE2 all potentiate pain through sensitization of afferent pain endings (the nerves that transmit impulses to the CNS and brain). Basically, these inflammatory mediators cause the body's pain receptors to become more sensitive. Quercetin, however, prevents the formation of those inflammatory mediators.
Allergies
Quercetin supplements counter allergic reactions by inhibiting enzymes responsible for the production of inflammatory mediators. Also, Quercetin inhibits histamine release by stabilizing basophils and mast cells. Quercetin is widely used by those who suffer from constant allergies (such as dust) and seasonal allergies (such as hay fever).
Cardiovascular Health
In a study that was released, a longitudinal investigation of risk factors for chronic diseases in elderly men revealed that high intakes of quercetin and other flavonoids predicted lower mortality rates and incidences of heart attack (myocardial infarction). Researchers in the Netherlands believe it is possible that quercetin and other flavonoids reduce the risk of heart disease by lowering the formation of plaque-building substances, specifically oxidized low-density lipoprotein (LDL).
Diabetic Complications
Many of the complications associated with diabetes, such as glaucoma, cataracts, and neuropathy, are caused by the sorbitol pathway, a process through which high levels of glucose are converted to sorbitol and fructose via the enzyme aldose reductase. In experimental animals, inhibitors of aldose reductase reduce the kidney and neurological symptoms shown to increase with diabetes. Quercetin is an established aldose reductase inhibitor.
The best quercetin supplements offer high-quality ingredients that have been tested and are highly bioavailable. When finding an appropriate quercetin dose, it's best to follow labelling directions on the manufacturer's label or your health care practitioner's advice.
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