Nicotinamide adenine dinucleotide (NADH) is a form of vitamin B3 (niacin) that is also sometimes called coenzyme 1. Your body can make this nutrient from dietary niacin or niacinamide. Because of this, deficiency is rare. NADH is necessary for the production of energy inside each of our body's cells. It also plays a role in the cellular repair of our DNA, the genetic template in each of our cells and the synthesis of some neurochemicals and hormones involved in brain and mental health.

Key Health Advantages of NADH/NAD

Energy and Metabolism

This nutrient increases the rate of chemical reactions in our mitochondria (the metabolic power plant of our cells) and alsohelps the cell repair the cellular genetic material (DNA). Any NADH in the body that is not currently in use for chemical reactions can act as an antioxidant, protecting the cells from damaging free radicals. Free radicals are unstable molecules with an unpaired electron that are extremely reactive, and damage surrounding cell membranes, fats, and fat-soluble vitamins and nutrients. Because of its role in metabolism, it is often used for conditions requiring an increase in energy and cellular repair.

Neurologic Effect and Mental Health

NADH also supports the production of certain neurochemicals and hormones in the body, such as adrenaline and dopamine. Low dopamine levels have been implicated in Parkinson's disease and possibly Alzheimer's disease, so increasing NADH may help to lower the risk of these conditions. Chronic fatigue syndrome is characterized by low energy and is also helped by taking a niacin supplement, perhaps because of increased adrenaline production. In general, ensuring adequate levels of this nutrient is a good step towards improving brain health and neurochemical balance. Thus, NADH can play a role in improved mental health and brain function.

Shopping For Quality NADH Supplements

This supplement can be found alone in capsules or tablets and is also found in combination formulas for energy enhancements. NADH can be directly supplemented at a dose between 2.5 and 10mg daily. Supplementation of niacin or niacinamide can allow the body to create the amount of NADH it needs naturally.

Potential Side Effects & Important Information

Doses greater than 5mg daily for prolonged periods have been shown to cause insomnia, anxiety, mood swings, and stomach upset. There are no known contraindications reported for the use of NADH.