Oregon Grape
Updated Aug. 15th, 2019
Oregon grape (Mahonia aquifolium) is an evergreen shrub that is closely related to Barberry. For more information on Barberry, please click here. Although it is called Oregon grape, this plant is not a true grape (Vitaceae) family, and has very different effects. The root has traditionally been used for hundreds of years by First Nations peoples in the treatment of a number of infections, as well as diarrhea and stomach ulcers. It is often used as an alternate to Goldenseal in herbal formulas when Goldenseal was not available, as both are rich in berberines. For more information on the benefits of Goldenseal, please click here.
Berberines
The main constituent of Oregon grape is a berberine, which gives this herb its antimicrobial and anti-inflammatory capabilities. Berberines have also been found to benefit in the treatment of: diabetes, Alzheimer's, depression, cardiovascular disease, and many types of cancer. For more information on the many benefits of berberines, please click here.
Preventing Multi-Drug Resistant Bacteria
Interestingly, the active constituents in Orgeon grape have been shown to inhibit the immunity of multi-drug resistant (MDR) bacteria, such as MRSA to antibiotics. These bacteria use a pump to shuttle the antibiotic back out of their cells as soon as it is absorbed. Oregon grape prevents the function of this pump, thus making the multi-resistant bacteria once again susceptible to prescription antibiotics. Because of this, it can be used in combination with antibiotics to help treat infections with these bacteria.
Psoriasis
It has been established by research that Orgeon grape applied topically in a 10% concentration to psoriasis lesions can significantly reduce their severity and can improve the quality of life of psoriasis sufferers. Some evidence suggests that taking it internally may help as well. Further research is required, but this has interesting potential.
How can I take Oregon Grape?
Oregon grape can be found in capsules or tablets on its own or in combination formulas for antimicrobial, and anti-diarrheal purposes. It can also be found in skin creams for the treatment of psoriasis. The oral dosage has not yet been established by research, so following the manufacturer's label instructions is best practice.
