Sytrinol is a patented, proprietary blend of nutrients developed by KGK Synergize. It's designed to support healthy blood cholesterol levels in those with elevated cholesterol. This unique formula combines specific plant extracts, vitamins, and minerals that work synergistically to promote cardiovascular health and maintain balanced lipid levels. By integrating these ingredients into daily routines, users may experience improved cardiovascular wellness and overall metabolic support.
Nutrients Found in Sytrinol
The proprietary blend contains 270mg of polymethoxyflavones extracted from Mandarin and/or bitter orange peel, and 30mg of tocotrienols extracted from palm oil.
Polymethoxyflavones (PMFs)
PMFs are a subgroup of citrus bioflavonoids, which have an extra methyl group. This class of molecules has been studied for their anti-inflammatory and cholesterol-loweringeffects. Some studies have shown these PMFs to lower LDL levels by inhibiting the synthesis of both apolipoprotein B and triglycerides. These two substances are the building blocks of the LDL particle, with apolipoprotein B making up almost 90% of most LDL.
Tocotrienols
These molecules are subtypes of vitamin E that are known to have anti-inflammatory and antioxidant activity. There is conflicting scientific evidence on whether tocotrienols successfully reduce cholesterol levels. Generally, in the scientific community, the beneficial effects of tocotrienols are considered to be due to their antioxidant ability, which can help to prevent the development of atherosclerosis. The tocotrienols used in this particular formula are extracted from palm oil.
Sytrinol Research
There are only 2 published research studies on Sytrinol at the moment, with a third still in process. The initial results of the research are promising, with reductions as follows:
Nutritional Information
| blood measurement | decrease relative to placebo group |
|---|---|
| total cholesterol | 20% – 30% |
| ldl ("bad" cholesterol) | 19% – 27% |
| apolipoprotein b (ldl subunit) | 21% |
| triglycerides | 24% – 34% |
For more information on what each of these measurements means, please see our high cholesterol article here.
The dose researched was 270mg per day of PMFs and 30mg per day of tocotrienols, which is their company's proprietary blend. This research appears extremely promising, although it is important to note that the two studies each consisted of only 10 people. Because of the extremely low number of people involved, it is difficult to be confident in the results of these studies. The tests were only performed for 12 weeks when the studies were published, so there is no evidence for the benefit longer than 3 months. The third, as of yet unfinished, study consists of 120 participants and is a longer-term study. The results of this will likely be more influential and will give a better idea of the benefits of this supplement. If it continues with the same results as its predecessors, this supplement may make statin medications obsolete!
Taking Sytrinol Supplements
This supplement has been studied at a dose of 150mg twice daily. It is not known how best to take this supplement beyond that limited information, due to a lack of research.
Important Information
Because it is a proprietary blend, there is very little research on the side effects and interactions of this medication. It is important that you speak with your healthcare professional before taking this if you are on any other medications or cardiovascular supplements. For the same reason, this supplement should not be used during pregnancy or breastfeeding.
