Digestion & IBS - 120 V-Caps

G.I. PRO GASTROINTESTINAL; relieves symptoms of irritable bowel syndrome and indigestion.
G.I. PRO GASTROINTESTINAL from CanPrev is a digestive formula designed to relieve symptoms of irritable Bowel Syndrome (IBS) and indigestion. G.I. PRO GASTROINTESTINAL contains a blend of herbs, nutrients and enzymes formulated to aid the complete digestion of food, decrease inflammation in the Gi tract, relieve stomach pains or spasms, protect the stomach, stimulate the liver and gallbladder and promote healing in the gastrointestinal tract.

Clinical Considerations
irritable Bowel Syndrome (IBS)
dyspepsia (indigestion)
Heartburn flatulence
Altered bowel patterns (constipation or diarrhea)
Abdominal pain or spasms
A bdominal distension (gas and/or bloating
Poor digestion
leaky Gut
F ood intolerances

Detailed Ingredient Descriptions & Benefits:

L-Glutamine is the most abundant amino acid in the bloodstream and the muscles of the body. it plays a very important role in digestion. the gastrointestinal tract is by far the greatest user of glutamine in the body. Supplemental glutamine has been shown to be helpful in the treatment of intestinal disorders and peptic ulcers. Glutamine is a form of metabolic fuel for the intestinal cells and it maintains the villi (the absorptive surfaces of the gut). it also nourishes the immune cells along the length of the gastrointestinal tract. Glu- tamine can help to restore normal tissue function and prevent intestinal permeability.

Quercetin
Quercetin belongs to a class of water-soluble plant colouring substances called biofla- vonoids. Quercetin has the ability to decrease inflammation by inhibiting inflammatory enzymes and stabilizing mast cells. this anti-inflammatory effect is important as researchers have found that abdominal pain or meal-related digestive symptoms may be the result of the activities and interactions of inflammatory factors such as mast cells, neural cells and eosinophils. the trigger for this inflammatory activity may be a pathogen, food, infection or allergen in the mucous membrane of the gastrointestinal tract. As well, in- dividuals who have allergic diseases such as asthma and allergic rhinitis often have gastrointestinal disorders such as iBS and medicinal ingredients with anti-inflammatory effects, such as quercetin, are valuable.

Artichoke extract has long been used in herbal medicine to help relieve digestive com- plaints such as dyspepsia. Artichoke increases the secretion of bile acids (from the liver and gallbladder) which helps decrease symptoms of bloating and fullness and aids digestion. the efficacy of artichoke leaf extract was evaluated in a randomized, open-label study of 516 healthy patients with self-reported dyspepsia. results of the study showed a reduction in dyspepsia scores of 40%. Holtman et al (2003) also conducted a randomized, double- blind, placebo-controlled trial to evaluate the efficacy of artichoke leaf extract in treating dyspepsia. Again, patients receiving the artichoke leaf extract had statistically significant decreases in the intensity of fullness, flatulence and early satiety after eating.

Angelica archangelica has historically been used in Herbal Medicine to aid digestion. in traditional use it has been shown to be helpful for colicky pains, gas, 'sour' stomach, gastric ulcers and bad breath. the German commission E has reported that angelica has anti- spasmodic and cholagogue actions and that it stimulates the secretion of gastric juices.

Bromelain is a natural anti-inflammatory enzyme that assists in breaking down proteins to further improve digestion. it is a proteolytic (protein-digesting enzyme) derived from pineapple juice pulp.

Curcumin is the main biologically active phytochemical compound of turmeric. turmeric is a spice derived from the rhizomes of curcuma longa, which has been used in Ayurvedic Medicine for centuries. turmeric is traditionally used in Herbal Medicine to help relieve flatulent dyspepsia and to aid digestion in general. it increases specific digestive enzyme factors (gastrin, secretin, pancreatic enzyme and bicarbonate), acts as a natural anti- inflammatory and reduces intestinal spasms. in a pilot study conducted by Bundy et al 2004,turmeric extract improved irritable Bowel Syndrome (iBS) symptoms in otherwise healthy adults by 25% after 8 weeks. turmeric is often formulated with bromelain for increased absorption and enhanced anti-inflammatory effects.

Peppermint extract is traditionally used in Herbal Medicine to aid digestion and relieve flatulent dyspepsia. More specifically, peppermint stimulates the flow of bile (from the liver and gallbladder) which relieves indigestion symptoms, inhibits unhealthy micro- organisms and reduces spasms. Animal studies have demonstrated a relaxation effect on gastrointestinal tissue. in human studies, the majority of clinical trials have been conducted using peppermint oil. However, abdominal pain and dyspepsia have been found to respond well to treatment with either peppermint leaves or oil.

Combination Rationale:
CanPrev's G.I. PRO GASTROINTESTINAL formulation is designed to work in a 'top down' fashion. ingre- dients in the formula work well with both the upper digestive organs (liver, gallbladder,
stomach and pancreas) and the lower digestive tract (the small and large intestines). G.I. PRO GASTROINTESTINAL contains nutrients, enzymes and herbs that stimulate the flow of bile from the liver and gallbladder, which improves digestion and reduces gas. Gentle herbs in the formula also calm abdominal pains or intestinal spasms, protect against ulcers and stabilize inflammatory factors in the intestines. As well, G.I. PRO GASTROINTESTINAL offers ingredients to improve the integrity of the gastrointestinal.

Directions: Adults - take three (3) capsules twice (2) daily with main meals (lunch and dinner) or as directed by a healthcare professional. for optimal effectiveness, digestion & iBS should be taken in conjunction with plenty of fibre and good quality probiotics (friendly bacteria) or fermented foods (e.g. yogurt, kefir). it is recommended that for the best possible results, G.I. PRO GASTROINTESTINAL should be taken for a minimum of 3 months. for long term use, periodic intervals of abstinence (2 week breaks) are recommended.

Cautions and Warnings
As with any natural health product, you should consult a healthcare practitioner on the use of this product especially if you are taking any medication including blood thinners or have a medical condition including anaemia, gallstones, bile duct obstruction, excess stomach acid, peptic ulcer or if you are on a low protein diet. consult a healthcare prac- titioner if symptoms persist or worsen. Avoid prolonged exposure to sunlight, ultraviolet light (uV) or uV therapy as ingredients may cause photosensitivity. do not use if seal is broken. Keep out of reach of children. do not use if you are pregnant or breastfeeding. mucosa so that it is less 'leaky' or permeable.