Now SAMe Stabilized 200mg - 60 V-Caps

Cautions & Warnings: Do not use if you have been diagnosed with bipolar disorder. Do not use this product within 2 weeks of discontinuing a Monoamine Oxidase Inhibitor (MAOI) drug. Consult a health care practitioner before use if you are taking any other medications. Do not use if you are pregnant or breastfeeding. Flatulence, nausea, vomiting, diarrhea, constipation, dry mouth, mild insomnia, sweating, dizziness and nervousness may occur.

WHAT IS SAMe?

S-adenosyl methionine (SAMe) is a form of the amino acid, methionine that is bonded with ATP, the major source of energy in the body. It works in three biochemical pathways. It was discovered in 1952 in Italy and has been researched and manufactured there. SAMe works closely with folic acid and vitamin B-12 and functions as a methyl donor. This nutrient carries and donates methyl molecules necessary to facilitate the manufacture of DNA and brain neurotransmitters. Tissue levels of SAMe are typically low in the elderly.

Research indicates that SAMe plays a vital role in nervous system health and normal cognitive function. SAMe may support nervous system function by increasing the synthesis and recycling of certain neurotransmitters and enhancing the sensitivity of nerve receptors. SAMe is believed to positively effect a number of neurotransmitters, including serotonin, dopamine, noradrenaline and norepinephrine. Although the mechanism for SAMe's impact upon neural function is not fully understood, there is no doubt that SAMe's capacity as a methyl donor is of critical importance.

As a methyl donor SAMe assists the body in the creation of complex organic compounds necessary for normal healthy function. Your body uses these new compounds for numerous purposes, including brain function and detoxification. This process, known as methylation or transmethylation, is vital to your body's maintenance. SAMe may be the most effective of all methyl donors discovered to date. Research has shown that SAMe is the only methyl donor with the potential to increase transmethylation in the brain, which helps to protect it from homocysteine damage as well as increasing production of glutathione, one of the body's most effective antioxidants.

SAMe & Folic Acid

Research into the biosynthesis of SAMe has established a clear link between SAMe and folic acid, or folate. Folic Acid has been proven to provide support for healthy nervous system function and a healthy mood, and researchers believe these two nutrients work together to beneficially effect monoamine systems, which directly affect mood and cognitive function. SAMe has also been show to improve the synthesis of phospholipids for use in the brain, probably one of the most beneficial effects SAMe has on brain health.

Not Just For The Brain...

The benefits of SAMe extend beyond the brain and throughout the human body. For example, it may also aid in the repair of myelin, the sheath of fatty material that surrounds nerves and nerve cells everywhere in our nervous system. SAMe is found in all human tissue and organs and is available for use by your body in over 35 different biochemical reactions necessary for optimal health.

SAMe may support joint health through transulfuration, a process that takes a certain amount of sulfur from SAMe to create glucosamine and chondroitin sulfates. This enhances proteoglycan synthesis, the molecule responsible for keeping articular (joint) cartilage lubricated. As mentioned earlier, SAMe is also important for the production of glutathione, a powerful free radical scavenger that defends your body from toxic agents and is necessary for liver detoxification.