PS-100 - 60 V-Caps

PS-100 - 60 V-Caps

Sale: $43.08

Reg.: $53.77 (Save $10.69)

Availability: In stock online

+ Earn 43 FREE Reward Points Rewards Info>
PS-100 FROM AOR SUPPORTS A HEALTHY MIND.

AOR's PS-100 is phosphatidylserine, a phospholipid, which plays an essential role in brain cell membrane structure. Studies suggest that phosphatidylserine supplements support brain function. AOR's PS in nature works to serve as a building block for cell membranes. [VEGETABLE CAPSULE]

Order Options

OR
Order Code: aor1570
UPC: 624917040623
Free Shipping
Orders $79+

BE$T PRICE GUARANTEE

1 capsule contains:
100mg
SunPS® Phosphatidylserine (certified organic, cold pressed sunflower)
SunPS® is a registered trademark of ECA Health Care Inc.

Other ingredients:
Microcrystalline cellulose, silicon dioxide, sodium stearyl fumarate. Capsule: hypromellose.

Format

format thumbVeggie Caps

60 Vcaps

Dosage

Take one capsule three times daily with/without food, or as directed by a qualified health care practitioner.

Important Information

Contains no wheat, gluten, corn, nuts, peanuts, sesame seeds, sulphites, mustard, dairy, eggs, soy, fish or shellfish.

Highlights
  • Cognitive support.
  • Support cell membranes.
  • Memory
  • Soybean source.
  • Vegi-Caps.

Related Videos

No Related Videos

Articles by a naturopathic doctor.

Manufacturer Info

AOR Canada is the innovative formulators of Canada’s best-selling antioxidant support, AOR Advanced B Complex and AOR Tri-B12. They are also known for their top bone health supplements, Ortho Adapt and Bone Basics. You can also SHOP AOR's Nattokinase, and trusted Curcumin Ultra, Curcumin Active and Curcumin95 inflammation support at National Nutrition.ca. AOR are leaders in natural health with innovative product development.

"Time bears away all things, even our minds."

These words, penned by the Roman poet Virgil in 34 B.C., are adopting increasing significance for the privileged nations of the present. These nations, loosely referred to as the 'first world', have come to equate progress and prosperity with longer life-spans and lower birthrates, leading to an increasingly graying population. The maintenance of optimal health becomes increasingly challenging - but by no means insurmountable - as the aging process continues. One facet of health that is of paramount concern to seniors is of course cognitive function. The ability to think clearly and effectively has far-reaching implications for personal and professional productivity, self-esteem and independence, as even marginal cognitive deterioration can lead to distress and hardship.
Understandably, research is proceeding at a fast pace in this field, with the goal of alleviating neural deterioration at an early stage. Results from clinical trials conducted in the U.S. and Europe indicate that supplementation with phosphatidylserine (PS) can play an important role in the support of mental functions in the aging brain. PS is a phospholipid that is a structural component of biological membranes of plants, animals and other life forms. While PS is essential to the proper functioning of all cells, it is most concentrated in the brain and cerebral cortex. Supplemental PS was initially isolated from bovine brain but is now mainly extracted from soy lecithin. Phosphatidylserine is made up of a glycerophosphate frame linked to two fatty acid molecules and the amino acid L-serine.
Remember The Membrane
The primary biological role of PS in nature is to serve as a building block for cell membranes. Membranes are the complex outer layers of all cells. They are known as the 'gatekeepers' of the cells due to their role in determining what enters and exits the cell, and PS is a fundamental component of each and every cell membrane, effectively holding together the enzymes, transport molecules, ion pumps, receptors and other constituents of the membrane's complex matrix. Membranes in general, and neuronal membranes in particular, are far more than just gatekeepers. They are in fact the working surfaces of the cell - and they depend on PS to perform that role. They regulate such functions as:

  • Entry of nutrients to and exit of waste products from the cell; An example is PS's support for the activity of ATPase enzymes that regulate cellular sodium-potassium and calcium-magnesium balance.


  • Movements of charged atoms (ions) into and out of the cell; Neuronal cells rely heavily on ATPase enzymes for these movements, and PS has a particularly supportive association with ATPase enzymes, restoring them to youthful levels in aged laboratory rat models.


  • Cellular communications with extracellular environment and other cells; Cell membranes contain many different cell receptors that rely on enzymes which themselves rely on PS. These include olfactory bulbs and prolactin receptors, whose sensitivity and density was increased by PS in laboratory animal experiments. PS also plays a role in the preparation and release of secretory vesicles (membrane-bound organelles destined for a specific function via an extracellular process).


  • Cell movement, shape changes, contraction and expansion; Nerve growth factor (NGF) is one of the most important growth factors for nerve tissue. In animal studies, PS inhibited age-related NGF receptor decline, and stimulated NGF synthesis in-vitro.


All of the aforementioned functions are dependent on the operative and structural integrity of the membranes for their full functional capacity and coordinated activity, and PS plays an encompassing role in that operative and structural integrity, particularly of neuronal cell membranes.

Mechanism of Action

Studies among laboratory rats indicate that PS replenishes acetylcholine in the aging brain, a critical indicator considering that acetylcholine levels are severely depleted in Alzheimer's patients. PS appears to do this while simultaneously sparing choline for the further synthesis of acetylcholine. In order for these functions to be fully appreciated, it must be remembered that most drugs designed to treat Alzheimer's patients use the same principle, namely by increasing acetylcholine levels. Such drugs, known as reversible acetylcholinesterase inhibitors, perform this task by inhibiting the enzyme acetylcholinesterase that catalyzes the breakdown of acetylcholine. PS also stimulates the increased release of acetylcholine by restoring protein kinase C activity (an isoenzyme that facilitates acetylcholine production) in laboratory studies among aging rats. The dendritic neurons, located in the hippocampus of the brain and regarded as a substrate used to store and retrieve memories, tend to become more sparse and diluted with age - compromising cognitive capabilities as a result. Experiments with laboratory rats have revealed that treatment with PS prevents the age-related decline in dendritic neuron density. Furthermore, scientists believe that PS's cognitive-enhancing effects can also be attributed to it's stimulation of the uptake of calcium by brain neuronal synapses (essential to the transfer of excitatory impulses).

Research Synopsis
Studies have demonstrated that supplemental PS possesses the ability to alleviate cognitive impairment, with particular emphasis on the symptoms of Alzheimer's disease. There have been at least 70 published human studies with PS, approximately twenty of them being double-blind. In a landmark multicenter study of the effects of phosphatidylserine supplementation on Alzheimer's disease, 142 subjects aged 40 to 80 were given either 200 milligrams of PS per day or a placebo for a three-month period. According to the standardized test scores used to determine the severity of Alzheimer's disease, the subjects taking PS displayed 'statistically significant' improvements over the placebo group. Further Alzheimer's studies with PS supplementation have achieved similar results.

Clinical trials have also shown phosphatidylserine to be effective in other forms of cognitive dysfunction as well, including age-associated memory impairment and general dementia. Another multicenter study conducted among four universities (three in the US and the fourth in Italy) examined 149 subjects aged 50-75 who were suffering from varying degrees of memory impairment and were given either 300 mg of PS or a placebo for 12 weeks. The study group displayed significant improvements over the placebo group in the memory categories of: learning names and faces, recalling names and faces, facial recognition, telephone number recall, misplaced objects recall, paragraph recall, and the ability to concentrate while reading, conversing, and performing tasks. Interestingly, the most notable improvements were among the subjects who were relatively more memory-impaired. Another study used the same dosage regimen and duration, but with a smaller number of older volunteers (51 subjects with a median age of 71). The results were similar to the aforementioned study, with improvements being noted in as early as three weeks. Studies conducted across the U.S. and Europe have also reported similar results. One key Italian study in 1995 remains the largest and longest running double-blind trial with PS, involving 425 subjects (median age 77 years) across 23 institutions and running six months in duration. It too, followed a dosage regimen of 300 mg daily. Memory scores in the fields of (1) Total Recall, (2) Long-Term Storage, (3) Long-Term Retrieval, and (4) Long-Term Retrieval Consistent were assessed in accordance with the standardized Buschke Selective Reminding Test. Predictably, the memory and learning scores were 'highly significant' (p
Finally, there have also been several studies examining phosphatidylserine's ability to significantly reduce levels of the hormone cortisol, released by the body in response to stress. This capability has been of particular interest to athletes, but more recent research has focused on the connection between lower cortisol levels and elevated mood. This connection, combined with yet further clinical findings - including those revealing improved EEG alpha-rhythms - serve to establish the overall impact of phoshatidylserine in the global enhancement of brain performance, particularly on the aging brain
What People Are Saying:
  • Reviews
  • POST A NEW REVIEW
First name is required!
Last name is required!
First name is not valid!
Last name is not valid!
Please enter a valid email address.
Email address is required!
This email is already registered!
Password is required!
Enter a valid password!
Please enter 6 or more characters!
Please enter 16 or less characters!
Please ensure your passwords match.
Terms and Conditions are required!
Incorrect FormKey!
Incorrect Email or Password!
reCAPTCHA is mandatory. Click check box beside I am not a robot
Invalid login/register data, Kindly contact customer service agent.