Phosphatidyl Choline (Pc)
Updated Nov. 11th, 2024 | Read Time: 2 Minutes | What You Will Learn:
- How Phosphatidyl Choline Works In The Body
- Phosphatidyl Choline Supplement Varieties
- Key Considerations
- Nutritional Information
- Reader Comments (2)
Phosphatidyl choline (PC) is used in the food industry as a food emulsifier. Emulsifying means that it makes fat-soluble in water. As a supplement, PC breaks down fats, builds the cellular membrane and synthesizes the neurochemical acetylcholine.
How Phosphatidyl Choline Works In The Body
PC’s emulsifying properties prevent fatty build-ups in the body, for example in the blood vessels, gallbladder and liver. Decreasing fatty build-up in arteries helps to regulate blood pressure. PC is a large component of all cell membranes because it regulates the passage of substances into and out of the cell. It can cross the blood-brain barrier to produce brain chemicals (neurotransmitters) that aid in memory - in particular acetylcholine.
The protective coating of the brain and nerve cells is also composed of choline. In this respect PC helps to make the sheath (myelin) that surrounds the nerves that conduct messages from the brain to the muscles and organs of your body, performing a similar function to the insulation sheathing of electrical wires. If this protective sheath degenerates (as in MS), a "shorting out" of the message that the nerve is carrying occurs. Natural health practitioners for alcoholic liver damage, Alzheimer’s disease, gallstones, hepatitis, atherosclerosis, memory loss, nerve degeneration and depression recommend PC.
Phosphatidyl Choline Supplement Varieties
PC supplements are made in capsules but lecithin is found in capsules or as granules. Lecithin granules should be refrigerated for freshness because the essential fatty acid component can go rancid. Lecithin contains 10-20% PC. Newer lecithin supplements, made from fresh egg yolk, contain a higher percentage of PC.
Key Considerations
Oral contraceptives, estrogen, sulfa drugs, food processing, coffee and alcohol deplete lecithin in the body, which contains PC. Do not use high doses of lecithin if you have manic-depressive disorder.




Wow! So many times, I have heard about adverse health effects from emulsifiers such as disruption of the gut microbiome. It is interesting (and awesome!!) that phosphatidyl choline is an emulsifier that has utility in food products AND CAN BENEFIT HEALTH. I wonder: why are emulsifiers such as carageenan and guar gum, which have clear adverse health effects, used when pc seems to be a better alternative?: is pc more expensive? Or, does pc have adverse effects that are beyond the scope of your discussion?
Hello Rachel,
Thank you for your comment, it's nice to see our article has ignited these questions for you to further research. Since you mentioned guar gum, you can learn more about it here: https://www.nationalnutrition.ca/articles/supplements/guar-gum/
Have a healthy day.